E-mail: ku. However, short series or individual case reports have identified this tumour in the maxilla, mandible, breast tissue and thymus. Mucoepidermoid carcinoma originates from minor salivary glands, and it is therefore surprising that it is not more commonly seen in the tonsil. To date, we believe there has been only one previously reported case in the world literature of mucoepidermoid carcinoma occurring in the tonsil 1. We present a very rare case of mucoepidermoid carcinoma arising from within the structure of the palatine tonsil, rather from the adjacent pharyngeal wall, together with a short review of the literature.
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E-mail: ku. However, short series or individual case reports have identified this tumour in the maxilla, mandible, breast tissue and thymus. Mucoepidermoid carcinoma originates from minor salivary glands, and it is therefore surprising that it is not more commonly seen in the tonsil. To date, we believe there has been only one previously reported case in the world literature of mucoepidermoid carcinoma occurring in the tonsil 1.
We present a very rare case of mucoepidermoid carcinoma arising from within the structure of the palatine tonsil, rather from the adjacent pharyngeal wall, together with a short review of the literature. Tuttavia numerosi studi fanno riferimento a casi isolati in cui questo tipo di tumore origina dal mascellare, dalla mandibola, dalla ghiandola mammaria e dal timo. Fino ad oggi riteniamo sia stato precedentemente riportato in letteratura solo un caso di carcinoma mucoepidermoide nella tonsilla 1.
Presentiamo un caso molto raro di carcinoma muco epidermoide che originante dalla tonsilla palatina piuttosto che dalla adiacente parete faringea, insieme a una revisione dei casi riportati in letteratura. Introduction Mucoepidermoid carcinoma is the most common malignant salivary gland tumour 2 - 4. It has been reported in all ages with peak incidence at the 4th and 5th decades, with females affected more than males in a ratio.
It is the most frequent malignant salivary gland neoplasm in children 5. In the major salivary glands, Mucoepidermoid carcinoma demonstrates a broad spectrum of aggressiveness, which can be predicted by microscopic grading. High-grade tumours are highly aggressive and regional lymph node spread is common. The low-grade variant usually demonstrates a favourable outcome, but it is important to note that metastasis may also be present 7.
Distant metastasis is rare, but case reports of metastases to the lungs, brain, ovary and peritoneum have been reported 8. Histologically, the tumour is composed of mucous, basaloid, intermediate and epidermoid cells.
We present an unusual case of mucoepidermoid carcinoma arising in the tonsil. Case report A year-old male presented with an asymptomatic lump in the neck at level II. The lump was progressively increasing in size over 4 weeks. Intra-oral examination and flexible nasoendoscopy was normal.
A fine-needle aspiration cytology specimen showed malignant cells with no obvious architecture to determine the tissue of origin. Ultrasound detected the presence of a suspected necrotic node. A CT scan of the neck and chest confirmed a right-sided pathologic node at level II. No other abnormalities were evident. Examination under anaesthesia EUA was performed, which was suggestive of a bulky mass within the ipsilateral tonsil, and tonsillectomy was performed.
Biopsy confirmed a high-grade mucoepidermoid carcinoma arising from entirely within the substance of the ipsilateral tonsil, and not from the adjacent pharyngeal wall. Management involved complete tonsillectomy with ipsilateral neck dissection level II-IV.
Histology of the resected specimen confirmed metastatic carcinoma from the tonsil. He underwent postoperative radiotherapy.
The number of individuals diagnosed with cancer is increasing. In , around 1,, new cases of cancer were diagnosed in the USA and , will die due to the disease. Some of the most common cancers in are breast cancer, prostate cancer, melanoma of the skin, thyroid cancer, leukemia, kidney and renal pelvis cancer, bladder cancer and pancreatic cancer. This is due to lack of information about other types of cancer which are rare but can affect many people.
Carcinoma Mucoepidermóide – CME
Mucoepidermoid carcinomas have been reported at distant and atypical sites, including the breast, Eustachian tube of the ear, bronchi of the lungs, and thyroid. Reports of mucoepidermoid carcinomas of the subglottis are not common. Women are more commonly affected than men , and the mean age at onset is in the 5th decade of life. MEC is also the most common salivary gland malignancy in children. The tumor usually forms as a painless, fixed, slowly growing swelling of widely varying duration that sometimes goes through a phase of accelerated growth immediately before clinical presentation. Symptoms include tenderness, otorrhea, dysphagia, and trismus. Intraoral tumors are often bluish-red and fluctuant, and they may resemble mucoceles or vascular lesions.
Mucoepidermoid carcinoma of the tonsil: a very rare presentation